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Immunology Program Courses

Microbiology 204 Molecular and Cellular Immunology

This is an introductory graduate level course open to students from BMS, PIBS, Pharmaceutical Chemistry and other UCSF graduate programs.

Course Director

Anthony DeFranco
email: anthony.defranco@ucsf.edu
phone:(415) 476-5488

Topics
Mechanisms of immunoglobulin gene rearrangements, cell biology of antigen presentation to T-cells and of lymphocyte trafficking, antigen and cytokine receptor structure and signal transduction mechanisms, regulation of lymphocyte development and lymphocyte activation, mechanisms of cell-mediated killing of infected and neoplastic cells, whole organism immune response to infection, and diseases of the immune system, including allergy, autoimmunity, and AIDS.

Course D
etails
Course meets three times per week, Monday, Wednesday, and Friday from 1-2:30pm . The class will be broadcast to Mission Bay (room Gen. S-202). About 3/4 of the course will be lectures; the other 1/4 will be discussion sections. Please see the
calendar below for locations.

Grades will be based on participation in discussion sections and performance on take-home final exam.

Note: Lecture portion of the course is open to auditors. Auditors wishing to take part in the discussion sections must have prior consent of the instructor.

Prerequisites
None, but some background in molecular biology and cell biology would be useful.

Teaching Assistants
Megan McSweeney (megan.mcsweeney@ucsf.edu)


2009 Schedule

DAY
DATE
ROOM
LECTURE
LECTURER
DOWNLOADS
Friday 9/25 N-217/
GEN-S271
Overview of the Immune System DeFranco Download PPT
Monday 9/28 N-225/
GEN-S202
Innate Immunity
DeFranco Download PPT
Download Read List
Wednesday 9/30 N-217/
GEN-S202
Homing/Inflammation Cyster Download PPT
Friday 10/2 N-217/
GEN-S202

MHC/Antigen Presentation

Weiss

Download PPT
Download Read List

Monday 10/5 S-163 Discussion Hermiston

Instructions
Download Document
Online Journal

Wednesday 10/7 N-217/
(Mission Bay Viewing Cancelled
GEN-S271)

T Cell Antigen Receptors

Weiss

Download PPT
Download Read List

Friday 10/9 N-217/
GEN-S271

TCR Signaling

Weiss Download PPT
Download Read List
Monday 10/12

No Session
(BMS Retreat)

 
Wednesday 10/14 N-217/
GEN-S202
T Cell Development Weiss Download PPT
Download Read List
Friday 10/16

S-168

Discussion Matloubian  
Monday 10/19 HSW-300/
GEN-S202
Antibodies/Ig Genes DeFranco Download PPT
Download Read List
Wednesday 10/21 N-217/
GEN-S271
B Cell Development & Tolerance DeFranco Download PPT
Download Read List
Friday 10/23

No Session
(Immuno Retreat)
 
Monday 10/26 S-163

Discussion

Matloubian  
Wednesday 10/28 N-217/
GEN-S202
Anatomy of Immune Responses Cyster Download PPT
Friday 10/30 N-217/
GEN-S271

B Cell Activation

Cyster Download PPT
Monday 11/2 N-225/
GEN-S202
T Cell Activation Anderson  
Wednesday 11/4 N-217/
GEN-S202
Cytokines/Th1/Th2
Locksley Download PPT
Friday 11/6 S-180 Discussion Hermiston  
Monday 11/9 N-217/
GEN-S202
Effector T cell Functions Lanier

Download PPT
Download Read List

Wednesday 11/11 No Session
(Veteran's Day)
   
Friday 11/13

N-217/
GEN-S202

T Cell Tolerance Anderson  
Monday 11/16 N-217/
GEN-S202
Autoimmunity Anderson
Wednesday 11/18 N-217/
GEN-S202
NK Cell Recognition
Lanier Download PPT
Download Read List
Friday 11/20 N-217/
GEN-S202
Defense against Bacteria/Parasites Locksley Download PPT
Monday 11/23 N-217/
GEN-S202
Defense against Viruses/Aids Locksley  
Wednesday 11/25 S-157 Discussion
Lowell

 

Friday 11/27 (THANKSGIVING HOLIDAY)  
Monday 11/30 N-217/
GEN-S202
Allergy and Asthma Locksley  
Wednesday 12/2 S-168 Discussion Lowell
 
Friday 12/4 N-217/
GEN-S202
Tumor Immunity/ Immunotherapy Lanier

Download PPT
Download Read List

 


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